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With the release of iOS 5 for the iPhone and iPad this fall, Apple will bring the Nitro JavaScript engine to full-screen Web applications saved to a user's home screen.



From Apple Insider:
Currently, full-screen Web applications fail to use the Nitro acceleration Apple added to iOS 4.3. This can result in Web applications designed for the iPhone running much slower when saved to a home screen than they would if launched directly through the Mobile Safari browser.

But as highlighted on Thursday by CNet, the bug present in current version of iOS has been fixed in the first beta of iOS 5 delivered to developers. According to people familiar with the software, the Web.app feature in iOS 5 now has access to the Nitro JavaScript engine.
  iOS 5 supports speedy Nitro JavaScript for full-screen Web apps